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To quantity the GSH metabolism status and stratify THCA patients, we further constructed a 9-gene based signature via LASSO-penalized Cox regression model

4bd) show flow profiles indicating that a subset of ORS cells moves deeper into the hair bulb, while another subset switches direction and migrates directly outwards of the lower bulb region later forming the outer layers (Supplementary Fig

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Vitamin C regenerates oxidised glutathione back to its reduced form, and vitamin E protects cell membranes from lipid peroxidation that glutathione would otherwise need to address

Overall, our RNA-seq data revealed that hpr1-1 causes massive transcriptional reprogramming under high light, and deficient GLYR1 globally rescues hpr1-1 at the transcriptome level to a high extent, including transcriptional changes in genes related to photorespiration and photosynthesis and many other biological functions